Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BCL6 | P41182 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27987021 | 1.00 | STK17B (0.42) | STK17BSTK17ATDP1TP53MAPT | |
| SCHEMBL28814671 | 0.78 | STK17B (0.42) | STK17BSTK17ABCL6 | |
| SCHEMBL27987449 | 0.78 | ESR1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL27987018 | 0.78 | STK17B (0.42) | STK17BSTK17ABCL6 | |
| SCHEMBL1937173 | 0.74 | STK17A (0.41) | STK17BSTK17AALDH1A1BCL6 | |
| SCHEMBL1937307 | 0.72 | ESR1 (0.49) | STK17BSTK17ATP53MAPTSMN1; SMN2 | |
| SCHEMBL27620523 | 0.71 | RAB9A (0.38) | TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5246243 | 0.70 | STK17B (0.49) | STK17BSTK17AMAPTALDH1A1 | |
| SCHEMBL1935303 | 0.70 | STK17B (0.47) | STK17BSTK17AALDH1A1 | |
| SCHEMBL20652230 | 0.69 | STK17A (0.42) | STK17BSTK17AALDH1A1BCL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169272-A | Pyrimidine-2,4-diamine derivatives as kinase inhibitors | CELLZOME LTD | 2014-11-26 | — | — | CN | disclosed |