Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27988922 | 0.77 | SIGMAR1 (0.46) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6844898 | 0.76 | NOTUM (0.45) | LMNAMAPTTDP1TP53SMN1; SMN2 | |
| SCHEMBL2951878 | 0.75 | ALDH1A1 (0.66) | LMNAMAPTTDP1TP53SMN1; SMN2 | |
| SCHEMBL27989186 | 0.73 | LIPG (0.36) | LMNAMAPTTDP1TP53SMN1; SMN2 | |
| SCHEMBL15714684 | 0.72 | MYC (0.85) | LMNASMN1; SMN2MAPK1TSHRKDM4E | |
| SCHEMBL16599638 | 0.69 | GRM5 (0.49) | LMNAMAPTTDP1TP53SMN1; SMN2 | |
| SCHEMBL27320988 | 0.69 | IP6K1 (0.50) | LMNAMAPTTP53SMN1; SMN2NPC1 | |
| SCHEMBL1336438 | 0.69 | CHEK1 (0.51) | LMNAMAPTTP53SMN1; SMN2NPC1 | |
| SCHEMBL10373626 | 0.69 | MAPT (0.77) | LMNAMAPTTDP1TP53SMN1; SMN2 | |
| SCHEMBL632109 | 0.69 | CA12 (0.69) | LMNATP53SMN1; SMN2MAPK1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104203928-A | Triazinone compound and T-type calcium channel inhibitor | NISSAN CHEMICAL IND LTD | 2014-12-10 | — | — | CN | disclosed |