Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 3/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28768714 | 0.74 | HTR5A (0.41) | CREBBPBRPF1MEN1KMT2AMAPT | |
| SCHEMBL1600166 | 0.74 | CREBBP (0.40) | CREBBPBRPF1MEN1KMT2AMAPT | |
| SCHEMBL27759712 | 0.72 | CREBBP (0.39) | CREBBPBRPF1MEN1KMT2AMAPT | |
| SCHEMBL27321647 | 0.70 | CREBBP (0.38) | CREBBPBRPF1MEN1KMT2AMAPT | |
| SCHEMBL6422711 | 0.70 | MEN1 (0.36) | CREBBPBRPF1MEN1KMT2AMAPT | |
| SCHEMBL3319641 | 0.69 | CREBBP (0.39) | CREBBPBRPF1MEN1KMT2AMAPT | |
| SCHEMBL27322746 | 0.69 | MEN1 (0.33) | CREBBPMEN1KMT2AMAPTGAA | |
| SCHEMBL17376745 | 0.67 | CREBBP (0.42) | CREBBPBRPF1MEN1KMT2AMAPT | |
| SCHEMBL27520511 | 0.66 | MEN1 (0.35) | CREBBPBRPF1MEN1KMT2AMAPT | |
| SCHEMBL13834469 | 0.65 | KMT2A (0.68) | MEN1KMT2AMAPTNPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884693-A | Parasiticidal Compositions Comprising Benzimidazole Derivatives, Methods And Uses Thereof | 梅里亚有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-104203928-A | Triazinone compound and T-type calcium channel inhibitor | NISSAN CHEMICAL IND LTD | 2014-12-10 | — | — | CN | disclosed |