Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 5/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367031 | 0.75 | CREBBP (0.45) | CREBBPMEN1KMT2ABRD4ALDH1A1 | |
| SCHEMBL28805368 | 0.73 | KDM4E (0.38) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL6422711 | 0.70 | MEN1 (0.36) | CREBBPBRPF1MAPTMEN1KMT2A | |
| SCHEMBL6926769 | 0.69 | CREBBP (0.34) | CREBBPBRPF1MAPTMEN1KMT2A | |
| SCHEMBL17376745 | 0.67 | CREBBP (0.42) | CREBBPBRPF1MAPTMEN1KMT2A | |
| SCHEMBL29576846 | 0.66 | CREBBP (0.47) | CREBBPBRPF1MAPTMEN1KMT2A | |
| SCHEMBL14899877 | 0.66 | MAPT (0.37) | CREBBPBRPF1MAPTMEN1KMT2A | |
| SCHEMBL28482218 | 0.66 | TSHR (0.44) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL348705 | 0.64 | MAPT (0.50) | CREBBPMAPTGAABRD4EP300 | |
| SCHEMBL1601253 | 0.64 | RAB9A (0.33) | MAPTMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699007-A | New crystal form of flibanserin, preparation method and application thereof | 孟晓明 | 2018-10-23 | — | — | CN | claimed |
| CN-104093715-B | 4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives | 埃科特莱茵药品有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-104744476-B | IMIDAZOPYRAZINE Syk INHIBITORS | 吉利德康涅狄格公司 | 2017-04-12 | — | — | CN | claimed |
| CN-103382174-A | Cyclopropyl amine derivatives as histamin h3 receptor modulators | ABBOTT LAB | 2013-11-06 | — | — | CN | claimed |
| CN-101267825-B | benzodiazepine derivatives for treating hepatitis C infection | ARROW THERAPEUTICS LTD. (GB) | 2011-12-28 | — | — | CN | claimed |
| CN-101952267-A | Cyclopropylamine Derivatives | ABBOTT LAB | 2011-01-19 | — | — | CN | claimed |
| CN-101472887-A | Cyclopropylamine derivatives as modulators of the histamine H3 receptor | ABBOTT LAB (US) | 2009-07-01 | — | — | CN | claimed |
| CN-101267825-A | Benzodiazepine derivatives for treating hepatitis C infection | ARROW THERAPEUTICS LTD (GB) | 2008-09-17 | — | — | CN | claimed |
| CN-1933842-A | Pharmaceutical compositions comprising benzodiazepine derivatives and RSV fusion protein inhibitors | ARROW THERAPEUTICS LTD (GB) | 2007-03-21 | — | — | CN | claimed |
| CN-1057911-A | Form the coupling agent of weld and the color silver halide photographic-material that contains this coupling agent | FUJI PHOTO FILM CO LTD (JP) | 1992-01-15 | — | — | CN | claimed |
| CN-110776494-B | Benzyl piperidine-benzimidazole derivative or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-110776494-A | Benzyl piperidine-benzimidazole derivative or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2020-02-11 | — | — | CN | disclosed |
| CN-105622580-B | Benzimidazole as prolyl hydroxylase inhibitors | 詹森药业有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-106029076-B | Benzo piperazine composition as BET bromine domain inhibitor | 福马疗法公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-108699007-A | New crystal form of flibanserin, preparation method and application thereof | 孟晓明 | 2018-10-23 | — | — | CN | disclosed |
| CN-1347875-A | Novel cyclobutene diketone compound and its producing process, and pharmaceutical composition containing the same compound | SERVIER LAB (FR) | 2002-05-08 | — | — | CN | disclosed |
| CN-1272113-A | Lyxofuranosyl benzimidazoles as antiviral agents | UNIV MICHIGAN (US) | 2000-11-01 | — | — | CN | disclosed |
| CN-1043759-C | Alpha-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents | PFIZER (US) | 1999-06-23 | — | — | CN | disclosed |
| CN-1108674-A | Water-soluble azo compounds, preparation thereof, and use thereof as dyes | HOECHST AG (DE) | 1995-09-20 | — | — | CN | disclosed |
| CN-1057911-A | Form the coupling agent of weld and the color silver halide photographic-material that contains this coupling agent | FUJI PHOTO FILM CO LTD (JP) | 1992-01-15 | — | — | CN | disclosed |