Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TAF1 | P21675 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603746 | 0.83 | POLB (0.40) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL14861413 | 0.82 | BRD4 (0.32) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL2930014 | 0.80 | BRD4 (0.32) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL28328177 | 0.79 | GPR84 (0.31) | — | |
| SCHEMBL27628887 | 0.77 | MAPT (0.38) | POLBALDH1A1MAPT | |
| SCHEMBL6864577 | 0.77 | CDK4 (0.35) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL28328179 | 0.76 | — | — | |
| SCHEMBL5479286 | 0.75 | ALDH1A1 (0.38) | POLBALDH1A1MAPT | |
| SCHEMBL301397 | 0.72 | ALDH1A1 (0.35) | POLBALDH1A1MAPT | |
| SCHEMBL6049267 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483416-A | The synthetic method of the chloro- 3- alkyl uracil of 6- | SUZHOU HANDE CHUANGHONG BIOCHEMISTRY TECH CO LTD | 2019-11-22 | — | — | CN | disclosed |
| CN-103030631-B | Compound for preparing pyrimidinedione DPP-IV (dipeptidyl peptidase IV) inhibitors | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2014-12-10 | — | — | CN | disclosed |