Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603746 | 0.78 | POLB (0.40) | ALDH1A1POLBMAPT | |
| SCHEMBL14861413 | 0.77 | BRD4 (0.32) | ALDH1A1POLBMAPT | |
| SCHEMBL5290084 | 0.76 | ALDH1A1 (0.38) | ALDH1A1POLBMAPT | |
| SCHEMBL27628887 | 0.76 | MAPT (0.38) | ALDH1A1POLBMAPT | |
| SCHEMBL2930014 | 0.75 | BRD4 (0.32) | ALDH1A1POLBMAPT | |
| SCHEMBL27989702 | 0.75 | BRD4 (0.32) | ALDH1A1POLBMAPT | |
| SCHEMBL301397 | 0.71 | ALDH1A1 (0.35) | ALDH1A1POLBMAPT | |
| SCHEMBL28328179 | 0.71 | — | — | |
| SCHEMBL237871 | 0.71 | KMT2A (0.31) | — | |
| SCHEMBL28328177 | 0.71 | GPR84 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293517-A1 | Derivatives Of Chemotherapeutic Agents With A Formaldehyde Releasing Moiety | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2007-12-20 | — | — | US | disclosed |
| WO-2005120577-A2 | DERIVATIVES OF CHEMOTHERAPEUTIC AGENTS WITH A FORMALDEHYDE RELEASING MOEITY | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293517-A1 | Derivatives Of Chemotherapeutic Agents With A Formaldehyde Releasing Moiety | DHFR, FAU, MYD88 | ALDH1A1 234/4885POLB 1227/4885MAPT 3532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.