Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782005 | 0.82 | KDM4E (0.68) | KDM4EHSD17B10EPHX1KMT2AMEN1 | |
| SCHEMBL2388970 | 0.81 | EPHX1 (0.70) | KDM4EHSD17B10EPHX1KMT2AMEN1 | |
| SCHEMBL1249700 | 0.79 | KCNMA1 (0.64) | KDM4EHSD17B10KMT2AMEN1POLB | |
| SCHEMBL6106176 | 0.79 | GAA (0.63) | KDM4EHSD17B10KMT2AALDH1A1POLB | |
| SCHEMBL30296233 | 0.79 | KDM4E (0.59) | KDM4EHSD17B10EPHX1KMT2AMEN1 | |
| SCHEMBL9403860 | 0.79 | KDM4E (0.59) | KDM4EHSD17B10EPHX1KMT2AMEN1 | |
| SCHEMBL21214216 | 0.78 | HDAC1 (0.47) | KDM4EKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL30841749 | 0.78 | KDM4E (0.57) | KDM4EHSD17B10EPHX1KMT2AMEN1 | |
| SCHEMBL5042574 | 0.78 | KDM4E (0.57) | KDM4EHSD17B10EPHX1KMT2AMEN1 | |
| SCHEMBL9210058 | 0.78 | HDAC1 (0.58) | KDM4EHSD17B10EPHX1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104311508-B | Synthetic method of iron-catalyzed phenothiazine compound | 苏州大学 | 2017-01-11 | — | — | CN | claimed |
| CN-104311508-A | Synthetic method of iron-catalyzed phenothiazine compound | UNIV SOOCHOW | 2015-01-28 | — | — | CN | claimed |
| CN-104311508-B | Synthetic method of iron-catalyzed phenothiazine compound | 苏州大学 | 2017-01-11 | — | — | CN | disclosed |
| CN-104311508-A | Synthetic method of iron-catalyzed phenothiazine compound | UNIV SOOCHOW | 2015-01-28 | — | — | CN | disclosed |