Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805163 | 0.77 | ALDH1A1 (0.46) | HTTS1PR2S1PR4LMNANPSR1 | |
| SCHEMBL29288168 | 0.75 | HSD17B2 (0.41) | HTTS1PR2S1PR4LMNANPSR1 | |
| SCHEMBL29288167 | 0.75 | HSD17B2 (0.41) | HTTS1PR2S1PR4LMNANPSR1 | |
| SCHEMBL13826533 | 0.74 | ALDH1A1 (0.49) | HTTS1PR2S1PR4LMNANPSR1 | |
| SCHEMBL17914676 | 0.73 | ALDH1A1 (0.62) | LMNAMAPTALDH1A1MAPK1RAB9A | |
| SCHEMBL27990412 | 0.72 | MAPT (0.49) | HTTS1PR2S1PR4LMNANPSR1 | |
| SCHEMBL27990140 | 0.71 | NPC1 (0.46) | HTTLMNAMAPTALDH1A1HPGD | |
| SCHEMBL13719298 | 0.71 | MAPT (0.45) | HTTS1PR2S1PR4LMNANPSR1 | |
| SCHEMBL6875538 | 0.70 | SLC2A1 (0.43) | HTTLMNAMAPTALDH1A1HPGD | |
| SCHEMBL27357988 | 0.70 | PKM (0.52) | HTTMAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012381-B | Benzofuran compound, preparation method thereof and application of benzofuran compound in preparation of antiarrhythmic drugs | UNIV SHANDONG | 2015-01-07 | — | — | CN | disclosed |