Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28013542 | 0.98 | TSHR (0.48) | TSHRTP53NAPRTALDH1A1KDM4E | |
| Terephthalic Acid SCHEMBL28044877 | 0.98 | TSHR (0.48) | TSHRTP53NAPRTALDH1A1KDM4E | |
| Terephthalic Acid SCHEMBL28005997 | 0.98 | TSHR (0.48) | TSHRTP53NAPRTALDH1A1KDM4E | |
| Terephthalic Acid SCHEMBL28065968 | 0.98 | TSHR (0.48) | TSHRTP53NAPRTALDH1A1KDM4E | |
| Paraben SCHEMBL5369593 | 0.93 | CA2 (0.57) | TSHRTP53NAPRTALDH1A1KDM4E | |
| Terephthalic Acid SCHEMBL28600607 | 0.93 | TSHR (0.43) | TSHRTP53NAPRTALDH1A1KDM4E | |
| Benzoic Acid SCHEMBL17495601 | 0.92 | NAPRT (0.54) | TSHRTP53NAPRTALDH1A1KDM4E | |
| Terephthalic Acid SCHEMBL27990425 | 0.89 | TSHR (0.42) | TSHRTP53NAPRTALDH1A1KDM4E | |
| SCHEMBL28054671 | 0.88 | KDM4E (0.49) | TSHRALDH1A1KDM4ECA1CA2 | |
| Terephthalic Acid SCHEMBL28067237 | 0.88 | TSHR (0.45) | TSHRTP53NAPRTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610380-B | Triazole terephthalic acid (TPA) cobalt complex of phenyl triiodide amine three with potential fluorescent material and preparation method thereof | 天津师范大学 | 2017-08-11 | — | — | CN | claimed |
| CN-106187925-A | The double triazole terephthalic acid compounds monocrystalline of 4H thioether and application | 天津师范大学 | 2016-12-07 | — | — | CN | claimed |
| CN-104610324-B | There are phenyl triiodide amine three triazole terephthalic acid (TPA) cadmium complexes of potential fluorescent material and preparation method thereof | TIANJIN NORMAL UNIVERSITY (CN) | 2016-05-18 | — | — | CN | claimed |
| CN-105566359-A | 1,4-dimethyl-2,5-dimethylene bis(triazole) zinc terephthalate complex monocrystal and applications thereof | UNIV TIANJIN | 2016-05-11 | — | — | CN | claimed |
| CN-105524085-A | 1, 4-dimethyl-2, 5-dimethylene bistriazole terephthalic acid three-dimensional zinc complex single crystal and application thereof | UNIV TIANJIN | 2016-04-27 | — | — | CN | claimed |
| CN-105524088-A | Anthracycline bistriazole terephthalic acid inclusion diethyl formamide zinc complex single crystal and application thereof | UNIV TIANJIN | 2016-04-27 | — | — | CN | claimed |
| CN-105524086-A | Potential fluorescent material tetraphenyl ethylene tetra-triazole terephthalic acid zinc complex and preparation method thereof | UNIV TIANJIN | 2016-04-27 | — | — | CN | claimed |
| CN-105418523-A | 1,4-dimethyl-2,5-dimethylene bis(triazole)terephthalic acid single crystal and application | UNIV TIANJIN | 2016-03-23 | — | — | CN | claimed |
| CN-105294743-A | 4H sulfide double triazole terephthalic acid zinc complex single crystal and preparation method as well as application thereof | UNIV TIANJIN NORMAL | 2016-02-03 | — | — | CN | claimed |
| CN-104610299-A | Zinc naphthalene bistriazole terephthalic acid complex used as potential fluorescent material and preparation method thereof | UNIV TIANJIN NORMAL | 2015-05-13 | — | — | CN | claimed |
| CN-104610303-A | Zinc triiodo phenylamine tri-triazole terephthalic acid complex used as potential fluorescent material and preparation method thereof | UNIV TIANJIN NORMAL | 2015-05-13 | — | — | CN | claimed |
| CN-104610302-A | Antharcycline bis-triazole terephthalic acid zinc complex with potential fluorescent material and preparation method of antharcycline bis-triazole terephthalic acid zinc complex | UNIV TIANJIN NORMAL | 2015-05-13 | — | — | CN | claimed |
| CN-104610295-A | Potential fluorescent material containing tetraphenylethylene tetra-triazole zinc terephthalate complex and preparation method thereof | UNIV TIANJIN NORMAL | 2015-05-13 | — | — | CN | claimed |
| CN-104610380-B | Triazole terephthalic acid (TPA) cobalt complex of phenyl triiodide amine three with potential fluorescent material and preparation method thereof | 天津师范大学 | 2017-08-11 | — | — | CN | disclosed |
| CN-104610380-B | Triazole terephthalic acid (TPA) cobalt complex of phenyl triiodide amine three with potential fluorescent material and preparation method thereof | 天津师范大学 | 2017-08-11 | — | — | CN | disclosed |
| CN-104610380-B | Triazole terephthalic acid (TPA) cobalt complex of phenyl triiodide amine three with potential fluorescent material and preparation method thereof | 天津师范大学 | 2017-08-11 | — | — | CN | disclosed |
| CN-104610299-A | Zinc naphthalene bistriazole terephthalic acid complex used as potential fluorescent material and preparation method thereof | UNIV TIANJIN NORMAL | 2015-05-13 | — | — | CN | disclosed |
| CN-104610303-A | Zinc triiodo phenylamine tri-triazole terephthalic acid complex used as potential fluorescent material and preparation method thereof | UNIV TIANJIN NORMAL | 2015-05-13 | — | — | CN | disclosed |
| CN-104610302-A | Antharcycline bis-triazole terephthalic acid zinc complex with potential fluorescent material and preparation method of antharcycline bis-triazole terephthalic acid zinc complex | UNIV TIANJIN NORMAL | 2015-05-13 | — | — | CN | disclosed |
| CN-104610295-A | Potential fluorescent material containing tetraphenylethylene tetra-triazole zinc terephthalate complex and preparation method thereof | UNIV TIANJIN NORMAL | 2015-05-13 | — | — | CN | disclosed |