SCHEMBL27991306

SCHEMBL27991306

O=Cc1cnc2ccccc2n1.[H+].[H+]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
HPGD P15428 2/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PIM1 P11309 1/20 0.45
PDE10A Q9Y233 1/20 0.45
RAB9A P51151 6/20 0.44
NPC1 O15118 4/20 0.44
SMN1; SMN2 Q16637 5/20 0.42
KDM4E B2RXH2 4/20 0.42
GPR3 P46089 1/20 0.42
PAX8 Q06710 1/20 0.42
ERN1 O75460 1/20 0.42
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
THRB P10828 1/20 0.40
MAPT P10636 3/20 0.40
HTT P42858 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28747408 1.00 ALDH1A1 (0.46) ALDH1A1HPGDALOX15HSD17B10PIM1
SCHEMBL97699 0.98 ALDH1A1 (0.47) ALDH1A1HPGDALOX15HSD17B10PIM1
Hydrochloric Acid SCHEMBL28114264 0.96 ALDH1A1 (0.46) ALDH1A1HPGDALOX15HSD17B10PIM1
SCHEMBL525672 0.80 PDE10A (0.50) ALDH1A1HPGDALOX15HSD17B10PIM1
SCHEMBL6852180 0.79 RAB9A (0.48) ALDH1A1HPGDALOX15HSD17B10PIM1
SCHEMBL6852174 0.79 RAB9A (0.48) ALDH1A1HPGDALOX15HSD17B10PIM1
SCHEMBL5845185 0.77 PDE10A (0.47) ALDH1A1HPGDALOX15HSD17B10PIM1
SCHEMBL896448 0.77 PDE10A (0.47) ALDH1A1HPGDALOX15HSD17B10PIM1
SCHEMBL3559408 0.77 PDE10A (0.47) ALDH1A1HPGDALOX15HSD17B10PIM1
SCHEMBL27321431 0.77 PDE10A (0.47) ALDH1A1HPGDALOX15HSD17B10PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102348684-B Ketoenoles substituted by haloalkylmethyleneoxyphenyl groups BAYER CROPSCIENCE AG 2014-11-12 CN disclosed