Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991306 | 0.98 | ALDH1A1 (0.46) | ALDH1A1HPGDALOX15HSD17B10PDE10A | |
| SCHEMBL28747408 | 0.98 | ALDH1A1 (0.46) | ALDH1A1HPGDALOX15HSD17B10PDE10A | |
| Hydrochloric Acid SCHEMBL28114264 | 0.98 | ALDH1A1 (0.46) | ALDH1A1HPGDALOX15HSD17B10PDE10A | |
| SCHEMBL525672 | 0.82 | PDE10A (0.50) | ALDH1A1HPGDALOX15HSD17B10PDE10A | |
| SCHEMBL6852180 | 0.80 | RAB9A (0.48) | ALDH1A1HPGDALOX15HSD17B10PDE10A | |
| SCHEMBL6852174 | 0.80 | RAB9A (0.48) | ALDH1A1HPGDALOX15HSD17B10PDE10A | |
| SCHEMBL5845185 | 0.78 | PDE10A (0.47) | ALDH1A1HPGDALOX15HSD17B10PDE10A | |
| SCHEMBL896448 | 0.78 | PDE10A (0.47) | ALDH1A1HPGDALOX15HSD17B10PDE10A | |
| SCHEMBL3559408 | 0.78 | PDE10A (0.47) | ALDH1A1HPGDALOX15HSD17B10PDE10A | |
| SCHEMBL27321431 | 0.78 | PDE10A (0.47) | ALDH1A1HPGDALOX15HSD17B10PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 717 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-113164459-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-113831330-B | New method for three-step synthesis of drug molecule 3- (2-thiophene-2-methylene) hydrazinoquinoxaline-2-ketone | 桂林理工大学 | 2024-02-06 | — | — | CN | claimed |
| CN-113861121-B | Novel method for generating 2, 3-dihydroxyquinoxaline and derivatives thereof through direct oxidation | 桂林理工大学 | 2023-11-17 | — | — | CN | claimed |
| CN-116789610-A | Photocatalytic preparation method of quinoxaline-2, 3-diketone compound | 湖南科技学院 | 2023-09-22 | — | — | CN | claimed |
| CN-111018795-B | Method for synthesizing quinoxaline-3-ketone under alkaline condition | 上海彩迩文生化科技有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-113620891-B | Method for preparing quinoxaline-2-ketone derivative by controllable catalysis | 浙江树人学院（浙江树人大学） | 2023-01-17 | — | — | CN | claimed |
| CN-114621983-B | Method for improving DHA (docosahexaenoic acid) yield of schizochytrium limacinum and preparation method of microbial oil | 南京师范大学 | 2022-08-16 | — | — | CN | claimed |
| CN-110218195-B | Stable isotope labeled quinoxaline-2-carboxylic acid and synthesis method thereof | 上海安谱实验科技股份有限公司 | 2022-08-09 | — | — | CN | claimed |
| CN-114621983-A | Method for improving DHA (docosahexaenoic acid) yield of schizochytrium limacinum and preparation method of microbial oil | 南京师范大学 | 2022-06-14 | — | — | CN | claimed |
| EP-0827507-B1 | PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES | BOEHRINGER INGELHEIM CA LTD (CA) | 1999-06-16 | — | — | EP | claimed |
| EP-0788360-A4 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | PROSCRIPT INC (US) | 1998-05-06 | — | — | EP | claimed |
| EP-0827507-A1 | PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1998-03-11 | — | — | EP | claimed |
| CN-1168633-A | Boronic ester and acid compounds, their synthesis and use | PROSCRIPT INC (US) | 1997-12-24 | — | — | CN | claimed |
| EP-0788360-A1 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | PROSCRIPT, INC. (US) | 1997-08-13 | — | — | EP | claimed |
| WO-1996031527-A1 | PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES | BOEHRINGER INGELHEIM (CANADA) LTD./BOEHRINGER INGELHEIM (CANADA) LTÉE. (CA) | 1996-10-10 | — | — | WO | claimed |
| US-5545640-A | VIRICIDES, HIV; AIDS | BIO-MEGA/BOEHRINGER INGELEHEIM RESEARCH INC. (CA) | 1996-08-13 | — | — | US | claimed |
| WO-1996013266-A1 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | PROSCRIPT, INC. (US) | 1996-05-09 | — | — | WO | claimed |
| US-5292737-A | Inhibit protein kinase activity; antiinflammatory/antitumor agents; treatment for cardiovascular disorders | SPHINX PHARMACEUTICALS CORPORATION (US) | 1994-03-08 | — | — | US | claimed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | claimed |