SCHEMBL27992005

SCHEMBL27992005

CCc1c(C)cccc1N.Cc1ccccc1[O]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
ATP4A P20648 2/20 0.42
ATP4B P51164 2/20 0.42
CD44 P16070 1/20 0.41
NOS3 P29474 1/20 0.38
NOS2 P35228 1/20 0.38
ALDH1A1 P00352 6/20 0.36
TSHR P16473 2/20 0.35
PIK3CA P42336 1/20 0.35
HSD17B10 Q99714 2/20 0.35
HEXA P06865 1/20 0.34
HEXB P07686 1/20 0.34
KDM4E B2RXH2 2/20 0.34
HPGD P15428 2/20 0.33
DHFR P00374 1/20 0.33
DPP4 P27487 1/20 0.33
KEAP1 Q14145 1/20 0.32
CYP2A6 P11509 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6344760 0.87 CD44 (0.52) CYP3A4TDP1ATP4AATP4BCD44
SCHEMBL30417664 0.87 CD44 (0.52) CYP3A4TDP1ATP4AATP4BCD44
Ethylene SCHEMBL27537107 0.83 CD44 (0.48) CYP3A4TDP1ATP4AATP4BCD44
SCHEMBL659716 0.78 NOS3 (0.38) CYP3A4TDP1NOS3NOS2ALDH1A1
SCHEMBL9638017 0.75 CYP3A4 (0.42) CYP3A4TDP1ATP4AATP4BCD44
SCHEMBL165995 0.74 GABRA1 (0.46) CYP3A4TDP1CD44ALDH1A1TSHR
SCHEMBL28136844 0.73 CD44 (0.36) CYP3A4TDP1ATP4AATP4BCD44
SCHEMBL434493 0.73 CYP3A4 (0.48) CYP3A4TDP1CD44NOS3NOS2
SCHEMBL49378 0.73
Ammonia Solution, Strong SCHEMBL7468688 0.72 GABRA1 (0.44) CYP3A4TDP1CD44ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104231659-A Red thiazole heterocyclic disperse dye compound containing benzoate group and preparation and application thereof YU XINGYING 2014-12-24 CN disclosed