SCHEMBL6344760

SCHEMBL6344760

CCc1c(C)cccc1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.52
CYP3A4 P08684 4/20 0.48
TDP1 Q9NUW8 3/20 0.48
NOS2 P35228 2/20 0.47
NOS3 P29474 1/20 0.47
TSHR P16473 3/20 0.46
PIK3CA P42336 1/20 0.46
ATP4A P20648 1/20 0.39
ATP4B P51164 1/20 0.39
ALDH1A1 P00352 5/20 0.38
HSD17B10 Q99714 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
HPGD P15428 1/20 0.36
DHFR P00374 1/20 0.36
DPP4 P27487 1/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30417664 1.00 CD44 (0.52) CD44CYP3A4TDP1NOS2NOS3
Ethylene SCHEMBL27537107 0.96 CD44 (0.48) CD44CYP3A4TDP1NOS2NOS3
SCHEMBL27992005 0.87 CYP3A4 (0.42) CD44CYP3A4TDP1NOS2NOS3
SCHEMBL434493 0.85 CYP3A4 (0.48) CD44CYP3A4TDP1NOS2NOS3
SCHEMBL3667054 0.83 CD44 (0.54) CD44CYP3A4TDP1NOS2NOS3
SCHEMBL8285148 0.82 NOS2 (0.50) CD44CYP3A4TDP1NOS2NOS3
SCHEMBL597056 0.82 CYP2A6 (0.45) CD44TDP1NOS2NOS3TSHR
SCHEMBL28136844 0.81 CD44 (0.36) CD44CYP3A4TDP1NOS2NOS3
SCHEMBL2009339 0.81 CD44 (0.52) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL31606366 0.81 CD44 (0.52) CD44CYP3A4TDP1TSHRPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107043318-B One kind recycling catalyst and its method for catalyzing and synthesizing chloroethanes from synthesis N, N- dicyanoethyl arylamine mother liquor CENTRAL SOUTH UNIVERSITY OF FORESTRY AND TECHNOLOGY (CN) 2019-11-01 CN claimed
CN-108395850-A Adhesive, two-component adhesive containing same, bonding method and combination 南通德恒光电科技有限公司 2018-08-14 CN claimed
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF KUMQUAT BIOSCIENCES INC. 2024-07-11 US disclosed
US-20240166846-A1 MARINE REPAIR COMPOSITION ILLINOIS TOOL WORKS INC. (US) 2024-05-23 US disclosed
EP-4337160-A1 DEVICE FOR THE OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2024-03-20 EP disclosed
EP-4271357-A1 SUBSTITUTION OF AMMONIA IN HAIR ALTERING PRODUCTS Advancion Corporation (US) 2023-11-08 EP disclosed
WO-2023180388-A1 2,4-DIOXOTETRAHYDROPYRIMIDINYL DERIVATIVES AS DEGRONS IN PROTACS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2023-09-28 WO disclosed
US-20230119573-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION APPARATUS, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2023-04-20 US disclosed
US-20230025076-A1 TRIARYL METHANE COMPOSITION, DYE COMPOSITION FOR OCULAR MEMBRANE DYEING D. WESTERN THERAPEUTICS INSTITUTE, INC. (JP) 2023-01-26 US disclosed
EP-4117609-A1 COMPOSITIONS FOR COLORING HAIR INCLUDING ULTRA-EFFICIENT HIGH AQUEOUS, MULTI-LAMELLAR EMULSION SYSTEMS, AND METHODS OF MAKING THE SAME Combe International LLC (US) 2023-01-18 EP disclosed
US-11534505-B2 Triaryl methane composition, dye composition for ocular membrane dyeing D. WESTERN THERAPEUTICS INSTITUTE, INC. (JP) 2022-12-27 US disclosed
EP-0003539-A2 N-Azolylalkyl-halogenoacetanilides, process for their preparation and their use as herbicides BAYER AG (DE) 1979-08-22 EP disclosed
US-4148799-A Process for the preparation of 2-aryliminothiazoline solutions BAYER AKTIENGESELLSCHAFT (DE) 1979-04-10 US disclosed
US-4147804-A ANTIARRHYTHMIA AGENTS WILLIAM H. RORER, INC. (US) 1979-04-03 US disclosed
US-4063881-A Synthetic polyamide fibres colored with acid azobenzene dyestuffs, containing a N-alkyl (or substituted alkyl)-n-sulphophenoxyalkylamino radical in the para position to the azo linkage PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-12-20 US disclosed
US-4040829-A SILVER HALIDE EMULSIONS, SEMI-DIFFUSIBLE COUPLER FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed
US-4036824-A Disazo dyestuffs containing A-O-alkylene-O-SO3 H group BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US disclosed
US-4029707-A VAPOR-PHASE REACTION OF AROMATIC AMINE WITH ALIPHATIC ALCOHOL EASTMAN KODAK COMPANY (US) 1977-06-14 US disclosed
US-4022762-A Water-soluble acid azo dyestuff containing a N-(p-sulphophenoxyalkyl)-N-alkyl amino group PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-05-10 US disclosed
US-3954997-A MITICIDES, INSECTICIDES THE UPJOHN COMPANY (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11534505-B2 Triaryl methane composition, dye composition for ocular membrane dyeing MB, ABCB11, NR1H4 CD44 4498/4885CYP3A4 117/4885TDP1 4414/4885
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF TP53, HRAS, KRAS CD44 712/4885CYP3A4 3742/4885TDP1 705/4885
US-20230025076-A1 TRIARYL METHANE COMPOSITION, DYE COMPOSITION FOR OCULAR MEMBRANE DYEING MB, ABCB11, NR1H4 CD44 4498/4885CYP3A4 117/4885TDP1 4414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.