Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 4/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15067572 | 0.83 | TAS1R3 (0.43) | CASP1KCNQ2LMNAHPGDSMN1; SMN2 | |
| SCHEMBL16054219 | 0.83 | TAS1R3 (0.43) | CASP1KCNQ2LMNAHPGDSMN1; SMN2 | |
| SCHEMBL16054482 | 0.83 | TAS1R3 (0.43) | CASP1KCNQ2LMNAHPGDSMN1; SMN2 | |
| SCHEMBL27992292 | 0.83 | TRPA1 (0.37) | CYP2D6LMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL15067585 | 0.83 | ADRB2 (0.45) | CASP1CTSAADRB2ADRB1CYP2D6 | |
| SCHEMBL15067895 | 0.83 | ADRB2 (0.45) | CASP1CTSAADRB2ADRB1CYP2D6 | |
| SCHEMBL15067442 | 0.83 | ADRB2 (0.45) | CASP1CTSAADRB2ADRB1CYP2D6 | |
| SCHEMBL15066249 | 0.82 | TAS1R3 (0.45) | TAS1R3TAS1R1 | |
| SCHEMBL15069770 | 0.82 | TAS1R3 (0.45) | TAS1R3TAS1R1 | |
| SCHEMBL16054408 | 0.82 | TAS1R3 (0.45) | TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419830-B | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes | 比皮艾思药物研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-104136416-B | Phenylalkylamino carbamate derivatives compound and comprise the pharmaceutical composition of this Phenylalkylamino carbamate derivatives compound | 比皮艾思药物研发有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105209027-A | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes | BIO PHARM SOLUTIONS CO LTD | 2015-12-30 | — | — | CN | disclosed |
| CN-104136416-A | Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same | BIO PHARM SOLUTIONS CO LTD | 2014-11-05 | — | — | CN | disclosed |