Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27993398 | 0.85 | ALDH1A1 (0.44) | MAPTALDH1A1SMN1; SMN2HTTTRPM8 | |
| SCHEMBL27993161 | 0.77 | PGK1 (0.45) | PGK1MAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL30154422 | 0.71 | MAPT (0.67) | PGK1MAPTHTTMAPK1L3MBTL1 | |
| SCHEMBL1978817 | 0.71 | MAPT (0.67) | PGK1MAPTHTTMAPK1L3MBTL1 | |
| SCHEMBL27993155 | 0.70 | CYP1A2 (0.51) | PGK1MAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL27993397 | 0.68 | PGK1 (0.45) | PGK1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11651996 | 0.67 | PGK1 (0.50) | PGK1MAPTMAPK1L3MBTL1 | |
| SCHEMBL13964060 | 0.67 | PGK1 (0.50) | PGK1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL28946168 | 0.67 | MAPT (0.60) | PGK1MAPTHTTMAPK1L3MBTL1 | |
| SCHEMBL28489675 | 0.66 | TXNRD1 (0.57) | PGK1MAPTHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104163791-A | N-pyridine (hetero) aryl amide compound and preparation method and application thereof | HUNAN RES INST CHEMICAL IND | 2014-11-26 | — | — | CN | claimed |
| CN-104163791-A | N-pyridine (hetero) aryl amide compound and preparation method and application thereof | HUNAN RES INST CHEMICAL IND | 2014-11-26 | — | — | CN | disclosed |