Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27887744 | 0.85 | CYP2A13 (0.43) | CYP2A13ALDH1A1KMT2AMAPTCYP3A4 | |
| SCHEMBL27871497 | 0.85 | CYP2A13 (0.43) | CYP2A13ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28120392 | 0.84 | MEN1 (0.41) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27818451 | 0.84 | MEN1 (0.41) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27993464 | 0.82 | SIRT2 (0.41) | ALDH1A1MAPTCYP3A4LMNATP53 | |
| SCHEMBL28800652 | 0.81 | KDM4E (0.43) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27887740 | 0.81 | SMN1; SMN2 (0.47) | CXCR4ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL27871495 | 0.81 | ACHE (0.45) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL28815714 | 0.80 | DRD4 (0.38) | CYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL27993712 | 0.78 | SIGMAR1 (0.43) | ALDH1A1MEN1KMT2AMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102675240-B | 4-substitute-2-hydroxy morpholine-3-ketone and preparation method thereof | ZHEJIANG HISUN PHARM CO LTD | 2015-01-14 | — | — | CN | disclosed |