Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15389016 | 0.87 | TSHR (0.41) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL7760077 | 0.80 | TSHR (0.50) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL3780613 | 0.73 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL16587420 | 0.72 | DYRK1A (0.41) | ALDH1A1KDM4EHPGDMAPTDYRK1A | |
| SCHEMBL3790582 | 0.72 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL4599675 | 0.69 | AR (0.50) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL25483123 | 0.69 | TAAR1 (0.39) | ALDH1A1KDM4EHPGDMAPTDYRK1A | |
| SCHEMBL102325 | 0.69 | TSHR (0.48) | ALDH1A1KDM4EHPGDDYRK1ATSHR | |
| SCHEMBL30602897 | 0.68 | L3MBTL1 (0.48) | ALDH1A1KDM4EMAPTKMT2ADYRK1A | |
| SCHEMBL1017994 | 0.68 | DAO (0.51) | KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379560-A | Benzamide derivative | CHUGAI PHARMACEUTICAL CO LTD | 2015-02-25 | — | — | CN | disclosed |
| CN-104379568-A | Quinazolinedione derivative | CHUGAI PHARMACEUTICAL CO LTD | 2015-02-25 | — | — | CN | disclosed |