Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15389016 | 0.88 | TSHR (0.41) | TSHRARMAPTMEN1KMT2A | |
| SCHEMBL27993496 | 0.80 | ALDH1A1 (0.40) | TSHRMAPTMEN1KMT2ATDP1 | |
| SCHEMBL31287953 | 0.80 | MAOA (0.51) | TSHRMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL20801750 | 0.80 | SCN4A (0.50) | TSHRMAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL8848578 | 0.79 | MAPK1 (0.37) | TSHRARMAPTMEN1KMT2A | |
| SCHEMBL6231963 | 0.79 | TSHR (0.56) | TSHRARMAPTMEN1KMT2A | |
| SCHEMBL15358060 | 0.71 | PKM (0.37) | TSHRARMAPTMEN1KMT2A | |
| SCHEMBL1922926 | 0.71 | TSHR (0.56) | TSHRARMAPTMEN1KMT2A | |
| SCHEMBL4599675 | 0.71 | AR (0.50) | TSHRARMAPTMEN1KMT2A | |
| SCHEMBL11498088 | 0.71 | TRPA1 (0.46) | TSHRMAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802862-B2 | 1,2-benzisothiazol-3-one compound production method | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2014-08-12 | — | — | US | disclosed |
| EP-2687519-A1 | 1,2-BENZISOTHIAZOL-3-ONE COMPOUND PRODUCTION METHOD | Sumitomo Seika Chemicals CO. LTD. (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-20130345433-A1 | 1,2-BENZISOTHIAZOL-3-ONE COMPOUND PRODUCTION METHOD | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2013-12-26 | — | — | US | disclosed |
| EP-1081141-A1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2001-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130345433-A1 | 1,2-BENZISOTHIAZOL-3-ONE COMPOUND PRODUCTION METHOD | BZW1, BZW2, NAT1 | TSHR 2656/4885AR 2782/4885MAPT 1801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.