Dl-Tryptophan

Dl-Tryptophan

SCHEMBL27994236

NC(Cc1c[nH]c2ccccc12)C(=O)O.O=CCCCC=O

nearest known ligand 0.80

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.80
MAPT P10636 3/20 0.80
KMT2A Q03164 3/20 0.80
LMNA P02545 2/20 0.80
TSHR P16473 2/20 0.80
BLM P54132 2/20 0.80
PMP22 Q01453 2/20 0.80
MEN1 O00255 2/20 0.80
MPO P05164 1/20 0.80
HIF1A Q16665 1/20 0.80
HTR1A P08908 2/20 0.60
HTR2A P28223 2/20 0.60
HTR2C P28335 2/20 0.60
SLC6A4 P31645 2/20 0.60
HTR7 P34969 2/20 0.60
HTR2B P41595 2/20 0.60
ALOX15 P16050 2/20 0.60
ALDH1A1 P00352 1/20 0.60
CYP3A4 P08684 1/20 0.60
ADORA3 P0DMS8 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan SCHEMBL3831274 0.90 KDM4E (0.89) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL27840618 0.90 KDM4E (0.89) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL27327550 0.90 KDM4E (0.89) KDM4EMAPTKMT2ALMNATSHR
D-Tryptophan SCHEMBL3829872 0.90 KDM4E (0.89) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL23141133 0.89 KMT2A (1.00) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL7327 0.89 KMT2A (1.00) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL4732052 0.89 KMT2A (1.00) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL475350 0.89 KMT2A (1.00) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL475349 0.89 KMT2A (1.00) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL289043 0.89 KMT2A (1.00) KDM4EMAPTKMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104353845-B The method of different-shape nano gold grain prepared by the tryptophan of pentanedial decoration 首都师范大学 2016-08-24 CN claimed
CN-104353845-A Method for preparing gold nanoparticles in different morphologies by using glutaraldehyde modified tryptophan UNIV CAPITAL NORMAL 2015-02-18 CN claimed
CN-104353845-B The method of different-shape nano gold grain prepared by the tryptophan of pentanedial decoration 首都师范大学 2016-08-24 CN disclosed
CN-104353845-B The method of different-shape nano gold grain prepared by the tryptophan of pentanedial decoration 首都师范大学 2016-08-24 CN disclosed
CN-104353845-A Method for preparing gold nanoparticles in different morphologies by using glutaraldehyde modified tryptophan UNIV CAPITAL NORMAL 2015-02-18 CN disclosed
CN-104353845-A Method for preparing gold nanoparticles in different morphologies by using glutaraldehyde modified tryptophan UNIV CAPITAL NORMAL 2015-02-18 CN disclosed