Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 3/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20600847 | 0.85 | BCHE (0.51) | IDO1TDO2CDK5CDK5R1CCNB2 | |
| SCHEMBL21070513 | 0.74 | MAPT (0.49) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL27977982 | 0.74 | AR (0.51) | IDO1TDO2ARCDK5CDK5R1 | |
| SCHEMBL29755083 | 0.74 | AR (0.51) | IDO1TDO2ARCDK5CDK5R1 | |
| SCHEMBL28569909 | 0.72 | AR (0.51) | IDO1TDO2ARCDK5CDK5R1 | |
| SCHEMBL27587648 | 0.71 | AR (0.76) | IDO1TDO2ARCDK5CDK5R1 | |
| SCHEMBL15162688 | 0.71 | AR (0.49) | IDO1TDO2ARCDK5CDK5R1 | |
| SCHEMBL27962668 | 0.69 | BCHE (0.60) | IDO1TDO2CDK5CDK5R1CCNB2 | |
| SCHEMBL4821347 | 0.69 | CCNB2 (0.68) | TDO2CDK5CDK5R1CCNB2CDK1 | |
| SCHEMBL20600867 | 0.69 | BCHE (0.56) | IDO1TDO2CDK5CDK5R1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102372693-B | Carbazole compound and application thereof | UNIV TSINGHUA | 2015-03-11 | — | — | CN | disclosed |