Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693791 | 0.90 | TP53 (0.52) | BLMPMP22KMT2AALOX15TP53 | |
| SCHEMBL29954549 | 0.79 | TET2 (0.46) | LMNAMAPTCYP1A2 | |
| SCHEMBL15776270 | 0.76 | — | — | |
| SCHEMBL29616703 | 0.76 | KMT2A (0.40) | BLMPMP22KMT2AALOX15ALOX5 | |
| SCHEMBL22595358 | 0.74 | ALOX15 (0.48) | BLMPMP22KMT2AALOX15ALOX5 | |
| SCHEMBL7384390 | 0.71 | ALOX15 (0.33) | BLMPMP22KMT2AALOX15 | |
| SCHEMBL9506053 | 0.71 | ALOX15 (0.33) | BLMPMP22KMT2AALOX15 | |
| SCHEMBL5673417 | 0.71 | ALOX15 (0.36) | BLMPMP22KMT2AALOX15ALOX5 | |
| SCHEMBL23704649 | 0.70 | — | — | |
| SCHEMBL15415082 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104250233-B | A kind of preparation method of 4-tertbutyloxycarbonyl-2-cyclopropyl morpholine | HUNAN HUATENG PHARMACEUTICAL Co.,Ltd. (CN) | 2016-03-16 | — | — | CN | disclosed |
| CN-104250233-A | 4-tert-butyloxycarboryl-2-cyclopropyl morpholine preparation method | Hunan huateng pharmaceutical co ltd | 2014-12-31 | — | — | CN | disclosed |