Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958288 | 0.82 | PNMT (0.47) | PNMTCES2HTR2AHTR2CHTR2B | |
| SCHEMBL20521478 | 0.82 | ACP3 (0.46) | PNMTCES2ACP3CTSLEPHX1 | |
| SCHEMBL27997011 | 0.80 | GPR139 (0.42) | SLC6A2 | |
| SCHEMBL28816371 | 0.79 | CYP11B1 (0.35) | PNMTL3MBTL1 | |
| SCHEMBL28816314 | 0.79 | CES2 (0.46) | PNMTCES2ACP3CTSLEPHX1 | |
| SCHEMBL3913019 | 0.77 | PNMT (0.47) | PNMTCES2HTR2AHTR2CHTR2B | |
| SCHEMBL11865382 | 0.76 | TSHR (0.50) | HTR2A | |
| SCHEMBL343403 | 0.74 | PNMT (0.61) | PNMTCES2HTR2AHTR2CHTR2B | |
| SCHEMBL1044909 | 0.74 | PNMT (0.61) | PNMTCES2HTR2AHTR2CHTR2B | |
| SCHEMBL1535283 | 0.74 | PNMT (0.61) | PNMTCES2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254522-A | Methanol derivatives as trpv3 modulators | ABBVIE INC | 2014-12-31 | — | — | CN | disclosed |