Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 5/20 | 0.32 |
| ▸ | MMP3 | P08254 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997194 | 0.85 | MMP8 (0.31) | MMP8MMP3MMP13ALDH1A1LMNA | |
| SCHEMBL28283711 | 0.77 | AKR1C3 (0.58) | AKR1C3NAMPTMMP8MMP3LMNA | |
| SCHEMBL27997385 | 0.72 | AKR1C3 (0.41) | AKR1C3NAMPTMMP8MMP3MMP13 | |
| SCHEMBL27736333 | 0.69 | TSHR (0.35) | OPRK1MAPT | |
| SCHEMBL28818277 | 0.68 | PSIP1 (0.35) | — | |
| SCHEMBL27520313 | 0.67 | CA1 (0.41) | KDM4EMAPT | |
| SCHEMBL13852961 | 0.67 | AKR1C3 (0.53) | AKR1C3NAMPTMMP8MMP3ALDH1A1 | |
| SCHEMBL18531205 | 0.67 | AKR1C3 (0.53) | AKR1C3NAMPTMMP8MMP3ALDH1A1 | |
| SCHEMBL12672361 | 0.67 | AKR1C3 (0.53) | AKR1C3NAMPTMMP8MMP3ALDH1A1 | |
| SCHEMBL27532362 | 0.64 | PSIP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579450-A | Novel indolizine compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2016-05-11 | — | — | CN | disclosed |
| CN-104341451-A | New phosphate compounds, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-02-11 | — | — | CN | disclosed |
| CN-104341395-A | Novel azole compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-02-11 | — | — | CN | disclosed |