Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27736333 | 0.74 | TSHR (0.35) | PSIP1CA12CA1CA2CA4 | |
| SCHEMBL27839481 | 0.73 | PSIP1 (0.50) | PSIP1CA12CA1CA2CA4 | |
| SCHEMBL27520313 | 0.72 | CA1 (0.41) | PSIP1CA12CA1CA2CA4 | |
| SCHEMBL28818276 | 0.68 | PSIP1 (0.36) | PSIP1CA12CA1CA2CA4 | |
| Ethane SCHEMBL28790923 | 0.68 | MEN1 (0.43) | CA1CA2CA7CA9 | |
| SCHEMBL27532362 | 0.68 | PSIP1 (0.31) | PSIP1 | |
| SCHEMBL28060151 | 0.68 | PSIP1 (0.31) | PSIP1 | |
| SCHEMBL27997387 | 0.68 | AKR1C3 (0.40) | — | |
| SCHEMBL28060198 | 0.68 | CA12 (0.30) | CA12CA1CA2CA4CA6 | |
| SCHEMBL27915239 | 0.66 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102176828-B | Antifungal preparation | SCYNEXIS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-104877001-A | Antifungal Agents | SCYNEXIS INC | 2015-09-02 | — | — | CN | disclosed |
| CN-102176827-B | Antifungal formulations | SCYNEXIS INC | 2015-05-20 | — | — | CN | disclosed |