Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997621 | 0.96 | ADORA2A (0.46) | ADORA2ADHODHADKCDK5CDK5R1 | |
| SCHEMBL17508367 | 0.88 | PIK3CG (0.40) | ADORA2ACDK5CDK5R1PIK3CDPIK3CA | |
| SCHEMBL27997390 | 0.80 | MAPK9 (0.49) | ADORA2AJAK2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL16218737 | 0.76 | ADORA2A (0.55) | ADORA2ADHODHJAK2ALDH1A1MEN1 | |
| SCHEMBL17522834 | 0.74 | KDM4E (0.50) | ADORA2ADHODHCDK5CDK5R1ALDH1A1 | |
| SCHEMBL14525924 | 0.73 | ALDH1A1 (0.50) | ADORA2AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14525863 | 0.73 | ALDH1A1 (0.50) | ADORA2AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27997397 | 0.71 | SMN1; SMN2 (0.44) | ALDH1A1KMT2ASMN1; SMN2LMNATP53 | |
| SCHEMBL30290940 | 0.70 | PIK3CA (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGMAP4K4 | |
| SCHEMBL14983464 | 0.69 | PIK3CG (0.65) | ADORA2AADKALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676767-B2 | Indoloacridine-containing derivative, preparation process and use thereof, and organic luminescent device | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2017-06-13 | — | — | US | disclosed |
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | AHR, CDYL, SLC18A1 | ADORA2A 101/4885DHODH 2327/4885ADK 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.