Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | NT5C2 | P49902 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17508366 | 0.88 | ADORA2A (0.43) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL27997621 | 0.88 | ADORA2A (0.46) | ADORA2ACDK5CDK5R1AKT2GSK3B | |
| SCHEMBL27997390 | 0.79 | MAPK9 (0.49) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL17522835 | 0.76 | ALDH1A1 (0.42) | ADORA2ANISCHPDE10ACDK5CDK5R1 | |
| SCHEMBL24596492 | 0.69 | ADORA2A (0.76) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL27997641 | 0.69 | PI4KA (0.43) | NISCHCDK5CDK5R1GSK3BMAPK11 | |
| SCHEMBL27997397 | 0.68 | SMN1; SMN2 (0.44) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL27997637 | 0.68 | CYP11B1 (0.41) | NISCHMAOA | |
| SCHEMBL20821003 | 0.67 | KMO (0.64) | PIK3CGPIK3CDPIK3CAPIK3CBPRKDC | |
| SCHEMBL11932672 | 0.67 | MKNK1 (0.46) | PIK3CAMAP4K4CDK5CDK5R1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676767-B2 | Indoloacridine-containing derivative, preparation process and use thereof, and organic luminescent device | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2017-06-13 | — | — | US | disclosed |
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | AHR, CDYL, SLC18A1 | PIK3CG 1181/4885PIK3CD 1004/4885PIK3CA 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.