Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 5/20 | 0.39 |
| ▸ | HRH1 | P35367 | 5/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27969757 | 0.86 | SMN1; SMN2 (0.42) | POLBSMN1; SMN2LMNAL3MBTL1TSHR | |
| SCHEMBL346648 | 0.83 | SMN1; SMN2 (0.56) | POLBSMN1; SMN2LMNAL3MBTL1TSHR | |
| SCHEMBL4195731 | 0.82 | POLB (0.55) | POLBSMN1; SMN2LMNAL3MBTL1TSHR | |
| SCHEMBL7002207 | 0.80 | ALDH1A1 (0.53) | POLBSMN1; SMN2LMNAL3MBTL1TSHR | |
| SCHEMBL23199851 | 0.79 | ALDH1A1 (0.47) | POLBSMN1; SMN2LMNAL3MBTL1TSHR | |
| SCHEMBL16748755 | 0.79 | ALDH1A1 (0.47) | POLBSMN1; SMN2LMNAL3MBTL1TSHR | |
| SCHEMBL27842859 | 0.78 | POLB (0.58) | POLBSMN1; SMN2LMNAL3MBTL1TSHR | |
| SCHEMBL29948489 | 0.78 | POLB (0.54) | POLBSMN1; SMN2LMNAL3MBTL1TSHR | |
| SCHEMBL30237085 | 0.77 | LMNA (0.50) | POLBSMN1; SMN2LMNAL3MBTL1TSHR | |
| SCHEMBL16391280 | 0.77 | ALDH1A1 (0.45) | POLBSMN1; SMN2LMNAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104302645-A | Antibacterial compounds | BIOTA EUROPE LTD | 2015-01-21 | — | — | CN | disclosed |