Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.43 |
| ▸ | ILK | Q13418 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687318 | 0.85 | ALDH1A1 (0.46) | ASH1LILKALDH1A1MAPTKMT2A | |
| SCHEMBL984327 | 0.83 | ILK (0.59) | ASH1LILKSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL260372 | 0.79 | ALDH1A1 (0.51) | ILKSMN1; SMN2ALDH1A1MAPTKMT2A | |
| Bromide SCHEMBL261347 | 0.78 | ALDH1A1 (0.50) | ILKSMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL19729156 | 0.77 | ALDH1A1 (0.53) | ILKSMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL74889 | 0.74 | PDPK1 (0.53) | ASH1LSMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL30003135 | 0.73 | SMN1; SMN2 (0.56) | ASH1LSMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL289210 | 0.73 | SMN1; SMN2 (0.56) | ASH1LSMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL23422372 | 0.72 | ELANE (0.44) | ASH1LSMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL20297657 | 0.72 | ASH1L (0.44) | ASH1LSMN1; SMN2ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104478828-A | 2-amino-7-substituted benzothiazole compound as well as preparation method and application thereof | ZHANGZHOU PIEN TZE HUANG PHARM | 2015-04-01 | — | — | CN | disclosed |