Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ILK | Q13418 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | CDC25C | P30307 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL261347 | 0.99 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRRAB9AMAPT | |
| SCHEMBL19729156 | 0.89 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TSHRRAB9AMAPT | |
| SCHEMBL31053715 | 0.85 | NPC1 (0.47) | ALDH1A1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL1553043 | 0.84 | TSHR (0.51) | ALDH1A1HSD17B10TSHRRAB9AMAPT | |
| SCHEMBL984327 | 0.84 | ILK (0.59) | ALDH1A1HSD17B10TSHRMAPTSMN1; SMN2 | |
| SCHEMBL6112936 | 0.83 | TSHR (0.50) | ALDH1A1HSD17B10TSHRRAB9AMAPT | |
| SCHEMBL27998626 | 0.79 | ASH1L (0.43) | ALDH1A1HSD17B10RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9722823 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TSHRRAB9AMAPT | |
| SCHEMBL687318 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HSD17B10RAB9AMAPTGAA | |
| SCHEMBL2824199 | 0.77 | PRKD3 (0.45) | ALDH1A1HSD17B10TSHRRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159561-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORP (US) | 2023-05-25 | — | — | US | disclosed |
| US-11578085-B2 | Heterocycle-substituted bicyclic azole pesticides | FMC CORPORATION (US) | 2023-02-14 | — | — | US | disclosed |
| EP-4105209-A2 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC Corporation (US) | 2022-12-21 | — | — | EP | disclosed |
| EP-3424919-B1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORP (US) | 2022-04-27 | — | — | EP | disclosed |
| CN-112679467-A | Heterocyclic substituted bicyclic azoles as pesticidal agents | FMC公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-107635984-B | Heterocyclic substituted bicyclic azoles as pesticidal agents | FMC公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-112608300-A | Heterocyclic substituted bicyclic azoles as pesticidal agents | FMC公司 | 2021-04-06 | — | — | CN | disclosed |
| US-20210017192-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORP (US) | 2021-01-21 | — | — | US | disclosed |
| US-10822351-B2 | Heterocycle-substituted bicyclic azole pesticides | FMC CORPORATION (US) | 2020-11-03 | — | — | US | disclosed |
| EP-3567036-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC Corporation (US) | 2019-11-13 | — | — | EP | disclosed |
| US-20090209579-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | XIE WENGE | 2009-08-20 | — | — | US | disclosed |
| US-7429664-B2 | Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-09-30 | — | — | US | disclosed |
| US-20080176890-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | XIE WENGE | 2008-07-24 | — | — | US | disclosed |
| US-20080154037-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | XIE WENGE | 2008-06-26 | — | — | US | disclosed |
| EP-1735306-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2006-12-27 | — | — | EP | disclosed |
| US-20050234095-A1 | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof | MEMORY PHARMACEUTICALS CORPORATION | 2005-10-20 | — | — | US | disclosed |
| WO-2005092890-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |
| EP-1543000-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20040132790-A1 | Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof | MEMORY PHARMACEUTICALS CORPORATION | 2004-07-08 | — | — | US | disclosed |
| WO-2004029050-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2004-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10822351-B2 | Heterocycle-substituted bicyclic azole pesticides | CYP4X1, DDT, CHRM1 | ALDH1A1 2441/4885HSD17B10 2978/4885TSHR 1382/4885 |
| US-20230159561-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | CYP4X1, DDT, CHRM1 | ALDH1A1 2441/4885HSD17B10 2978/4885TSHR 1382/4885 |
| US-20040132790-A1 | Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof | CHRNA5, CHRNA7, CHRNA3 | ALDH1A1 1431/4885HSD17B10 2432/4885TSHR 568/4885 |
| US-11578085-B2 | Heterocycle-substituted bicyclic azole pesticides | CYP4X1, DDT, CHRM1 | ALDH1A1 2441/4885HSD17B10 2978/4885TSHR 1382/4885 |
| US-20090209579-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | CHRNA7, CHRNA5, CHRNA3 | ALDH1A1 1268/4885HSD17B10 2300/4885TSHR 625/4885 |
| US-20080154037-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | CHRNA7, CHRNA5, CHRNA3 | ALDH1A1 1268/4885HSD17B10 2300/4885TSHR 625/4885 |
| US-20080176890-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | CHRNA7, CHRNA5, CHRNA3 | ALDH1A1 1268/4885HSD17B10 2300/4885TSHR 625/4885 |
| US-20210017192-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | CYP4X1, DDT, CHRM1 | ALDH1A1 2441/4885HSD17B10 2978/4885TSHR 1382/4885 |
| US-20050234095-A1 | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof | CHRNA7, CHRNA5, CHRNA3 | ALDH1A1 1806/4885HSD17B10 2288/4885TSHR 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.