Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360647 | 0.77 | NOTUM (0.56) | MAPTKDM4ENOTUMLMNAHTT | |
| SCHEMBL5255606 | 0.75 | MAPT (0.42) | MAPTKDM4ELMNAHTTALDH1A1 | |
| SCHEMBL27580807 | 0.74 | LMNA (0.44) | MAPTKDM4ENOTUMLMNAHTT | |
| SCHEMBL21008407 | 0.73 | MAPT (0.45) | MAPTKDM4ENOTUMLMNAHTT | |
| SCHEMBL8484510 | 0.73 | MAPT (0.45) | MAPTLMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL981641 | 0.70 | NOTUM (0.60) | MAPTNOTUMLMNAHTTALDH1A1 | |
| SCHEMBL29187748 | 0.70 | NOTUM (0.54) | MAPTKDM4ENOTUMLMNAALDH1A1 | |
| SCHEMBL5970502 | 0.69 | CHRNB4 (0.44) | ALDH1A1GAATDP1L3MBTL1HIF1A | |
| SCHEMBL397584 | 0.69 | NOTUM (0.57) | MAPTKDM4ENOTUMLMNAALDH1A1 | |
| SCHEMBL30911994 | 0.69 | L3MBTL1 (0.41) | MAPTKDM4ELMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104311469-A | Synthetic method of substituted indole-3-acetic acid | UNIV SOUTHEAST | 2015-01-28 | — | — | CN | disclosed |