Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4547538 | 0.84 | GAA (0.54) | KMT2AKDM4EL3MBTL1GAANPSR1 | |
| SCHEMBL3656942 | 0.72 | POLB (0.42) | KMT2AKDM4EL3MBTL1POLBLMNA | |
| SCHEMBL2157960 | 0.72 | SLC10A6 (0.45) | KMT2AL3MBTL1POLBLMNAHPGD | |
| SCHEMBL6285884 | 0.71 | KMT2A (0.56) | KMT2AKDM4EL3MBTL1LMNAMAPT | |
| SCHEMBL6561278 | 0.71 | MMP9 (0.61) | KMT2ANPSR1LMNAMAPTALDH1A1 | |
| SCHEMBL2748238 | 0.70 | CYP2C9 (0.46) | L3MBTL1GAANPSR1LMNAMAPT | |
| SCHEMBL532885 | 0.69 | LMNA (0.78) | KMT2AL3MBTL1NPSR1LMNAMAPT | |
| SCHEMBL2106418 | 0.68 | NPSR1 (0.42) | KMT2AL3MBTL1NPSR1POLBLMNA | |
| SCHEMBL20545868 | 0.68 | KMT2A (0.49) | KMT2AKDM4EL3MBTL1GAANPSR1 | |
| SCHEMBL25221412 | 0.66 | GAA (0.76) | KMT2AKDM4EL3MBTL1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334542-A | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors | CHIESI FARMA SPA | 2015-02-04 | — | — | CN | disclosed |