Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943030 | 0.81 | ALOX12 (0.49) | TSHRHDAC4HDAC2HDAC8GABRA1 | |
| SCHEMBL8943032 | 0.81 | ALOX12 (0.49) | TSHRHDAC4HDAC2HDAC8GABRA1 | |
| SCHEMBL6900092 | 0.80 | TSHR (0.52) | TSHRHDAC4HDAC2HDAC8GABRA1 | |
| SCHEMBL310186 | 0.80 | TSHR (0.52) | TSHRHDAC4HDAC2HDAC8GABRA1 | |
| SCHEMBL23491266 | 0.80 | TSHR (0.52) | TSHRHDAC4HDAC2HDAC8GABRA1 | |
| SCHEMBL560318 | 0.78 | TSHR (0.68) | TSHRHDAC4HDAC2HDAC8GABRA1 | |
| SCHEMBL560346 | 0.78 | TSHR (0.68) | TSHRHDAC4HDAC2HDAC8GABRA1 | |
| SCHEMBL561299 | 0.78 | TSHR (0.68) | TSHRHDAC4HDAC2HDAC8GABRA1 | |
| SCHEMBL202738 | 0.78 | TSHR (0.68) | TSHRHDAC4HDAC2HDAC8GABRA1 | |
| Hydrochloric Acid SCHEMBL7076051 | 0.77 | TSHR (0.65) | TSHRHDAC4HDAC2HDAC8GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507899-B | Phenol derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2016-11-30 | — | — | CN | disclosed |
| CN-104507899-A | Phenol derivative, preparation method and medical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-04-08 | — | — | CN | disclosed |