Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28000983 | 1.00 | CHRM1 (0.37) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL2681435 | 0.79 | CTSK (0.43) | CTSSCTSKCA2 | |
| SCHEMBL2681437 | 0.79 | CTSK (0.43) | CTSSCTSKCA2 | |
| SCHEMBL10830748 | 0.79 | CHRM1 (0.44) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL19946412 | 0.77 | PRSS1 (0.57) | HDAC1HDAC2PRSS1CTSGCTRB1 | |
| SCHEMBL16035447 | 0.76 | TAS1R3 (0.40) | PRSS1CTSGCTRB1CMA1CYP3A4 | |
| SCHEMBL27818659 | 0.76 | TAS1R3 (0.40) | PRSS1CTSGCTRB1CMA1CYP3A4 | |
| SCHEMBL28000732 | 0.76 | TAS1R3 (0.40) | PRSS1CTSGCTRB1CMA1CYP3A4 | |
| SCHEMBL19946418 | 0.76 | ALDH1A1 (0.51) | SLC6A3HDAC1HDAC2TDP1PRSS1 | |
| SCHEMBL27877776 | 0.72 | HPGD (0.42) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104761466-A | CHIRAL DIACYLHYDRAZINE LIGANDS FOR MODULATING EXPRESSION OF EXOGENOUS GENES VIA ECDYSONE RECEPTOR COMPLEX | INTREXON CORP | 2015-07-08 | — | — | CN | disclosed |