Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517539 | 0.89 | NISCH (0.41) | MAPTLMNAGAAPOLBNISCH | |
| SCHEMBL30205262 | 0.83 | NPC1 (0.45) | MAPTLMNAPOLBNISCHNPC1 | |
| SCHEMBL28002482 | 0.83 | LMNA (0.41) | MAPTLMNAGAAPOLBNPC1 | |
| SCHEMBL31012251 | 0.81 | NISCH (0.46) | MAPTLMNANISCHALOX15HSD17B10 | |
| SCHEMBL27921193 | 0.79 | NISCH (0.36) | MAPTLMNAGAANISCHNPC1 | |
| SCHEMBL27379957 | 0.76 | CYP19A1 (0.42) | MAPTLMNAGAANISCHRAB9A | |
| SCHEMBL27903425 | 0.75 | NISCH (0.46) | MAPTLMNAGAAPOLBNISCH | |
| SCHEMBL28002164 | 0.74 | NPC1 (0.47) | MAPTLMNAPOLBNISCHNPC1 | |
| SCHEMBL29546893 | 0.70 | EGFR (0.41) | MAPTLMNAGAANISCHNPC1 | |
| SCHEMBL17871058 | 0.69 | NOS3 (0.39) | MAPTLMNAGAAPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104496914-A | Synthesis method of 2-aryl-substituted quinazoline compounds | UNIV NORTHWESTERN | 2015-04-08 | — | — | CN | disclosed |