Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13194992 | 0.85 | KMT2A (0.56) | KMT2AMEN1ALDH1A1NPC1GAA | |
| SCHEMBL1713620 | 0.82 | GAA (0.51) | KMT2AMEN1ALDH1A1NPC1GAA | |
| SCHEMBL24323862 | 0.79 | HTR6 (0.47) | KMT2AMEN1ALDH1A1NPC1GAA | |
| SCHEMBL1868938 | 0.79 | F13A1 (0.66) | — | |
| SCHEMBL24057949 | 0.78 | POLB (0.56) | ALDH1A1SMN1; SMN2CHRM5POLB | |
| SCHEMBL8295952 | 0.77 | KMT2A (0.49) | KMT2AMEN1NPC1GAAMAPT | |
| SCHEMBL19658738 | 0.76 | NPY5R (0.56) | NPC1L3MBTL1ATM | |
| SCHEMBL2285784 | 0.75 | ALDH1A1 (0.76) | KMT2AMEN1ALDH1A1NPC1GAA | |
| SCHEMBL762416 | 0.75 | KMT2A (0.74) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL2015601 | 0.75 | GAA (0.61) | KMT2AMEN1ALDH1A1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103396399-B | Nitrogenated aromatic 6-membered ring derivative, and pharmaceutical agent comprising same | DAIICHI SANKYO CO LTD | 2015-04-29 | — | — | CN | claimed |