Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 5/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1154471 | 1.00 | DRD2 (0.44) | DRD2DRD3NR3C2TRPM8IDO1 | |
| SCHEMBL2422836 | 0.89 | UGT2B17 (0.47) | DRD2DRD3CYP11B1CYP11B2KDM4A | |
| SCHEMBL29625396 | 0.84 | HTR1A (0.48) | DRD2DRD3NR3C2CYP11B1CYP11B2 | |
| SCHEMBL19764959 | 0.84 | HTR1A (0.48) | DRD2DRD3NR3C2CYP11B1CYP11B2 | |
| SCHEMBL9274574 | 0.80 | CYP11B1 (0.38) | DRD2DRD3NR3C2POLLCYP11B1 | |
| SCHEMBL1508536 | 0.80 | OPRL1 (0.51) | IDO1POLLOPRL1KCNH2 | |
| SCHEMBL1151022 | 0.80 | OPRL1 (0.51) | IDO1POLLOPRL1KCNH2 | |
| SCHEMBL30997127 | 0.80 | OPRL1 (0.51) | IDO1POLLOPRL1KCNH2 | |
| SCHEMBL1746541 | 0.80 | OPRL1 (0.51) | IDO1POLLOPRL1KCNH2 | |
| SCHEMBL23948898 | 0.79 | S1PR1 (0.42) | NR3C2POLLCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104321319-A | New indanyloxydihydrobenzofuranylacetic acid derivatives and their use as GPR40 receptor agonists | BOEHRINGER INGELHEIM INT | 2015-01-28 | — | — | CN | disclosed |