SCHEMBL28003151

SCHEMBL28003151

Oc1c(Cl)ccc2ccc(F)nc12

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.34
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
DPP4 P27487 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
GRM4 Q14833 1/20 0.32
MEN1 O00255 1/20 0.32
ALOX15B O15296 1/20 0.32
NR1I2 O75469 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
HSP90AA1 P07900 1/20 0.32
CYP3A4 P08684 1/20 0.32
HTR1A P08908 1/20 0.32
ALOX5 P09917 1/20 0.32
MMP9 P14780 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28224552 0.78 PTPN22 (0.37) MAPTKDM4ELMNASMN1; SMN2ALDH1A1
SCHEMBL7935896 0.78 CRHBP (0.38) MAPTKDM4ELMNAHTTKMT2A
SCHEMBL1029075 0.75 MAPT (0.59) MAPTKDM4ELMNAHTTKMT2A
SCHEMBL16827263 0.75 MAPT (0.34) MAPTKDM4ELMNAHTTKMT2A
SCHEMBL28002859 0.75 MAPT (0.34) MAPTKDM4ELMNAHTTKMT2A
SCHEMBL5181213 0.75 KDM4E (0.32) KDM4ELMNAHTTKMT2ASMN1; SMN2
SCHEMBL12446255 0.74 CCR1 (0.43) MAPTKDM4ELMNAHTTSMN1; SMN2
SCHEMBL23548885 0.72 XPO1 (0.41) MAPTKDM4ELMNAHTTKMT2A
SCHEMBL12446257 0.71 SLC40A1 (0.34) RAB9AGRM4
SCHEMBL114706 0.69 KDM4E (0.58) MAPTKDM4ELMNAHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105828657-B Utensil for shaping fibrous material 宝洁公司 2019-07-16 CN claimed
CN-105828793-B Shaping keratin fibres using sugar 宝洁公司 2019-06-18 CN claimed
CN-105828791-B Keratin fiber is shaped using carbonic ester 宝洁公司 2019-09-20 CN disclosed
CN-105828787-B Shaping keratin fibres using oxoacetic acids and/or derivatives thereof 宝洁公司 2019-07-26 CN disclosed
CN-105828657-B Utensil for shaping fibrous material 宝洁公司 2019-07-16 CN disclosed
CN-105828793-B Shaping keratin fibres using sugar 宝洁公司 2019-06-18 CN disclosed
CN-107106450-A Shaping keratin fibres using arabinose and ethylene carbonate 宝洁公司 2017-08-29 CN disclosed
CN-107106438-A Process for shaping keratin fibres 宝洁公司 2017-08-29 CN disclosed
CN-106687009-A Structure modification apparatus 宝洁公司 2017-05-17 CN disclosed
CN-102428151-B Mix composition and the method for photocatalyst THE PROCTER & GAMBLE CO. (US) 2015-11-25 CN disclosed
CN-102648255-B Compositions and methods incorporating photocatalysts PROCTER & GAMBLE 2015-04-15 CN disclosed