Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16827263 | 0.78 | MAPT (0.34) | MAPTDPP4ALDH1A1KMT2AMEN1 | |
| SCHEMBL11002658 | 0.78 | PLAU (0.38) | ALDH1A1GAASLC40A1KDM4EHSP90AA1 | |
| SCHEMBL28002859 | 0.78 | MAPT (0.34) | MAPTDPP4ALDH1A1KMT2AMEN1 | |
| SCHEMBL5192042 | 0.78 | KDM4E (0.36) | MAPTALDH1A1KMT2AMEN1SLC40A1 | |
| SCHEMBL28003151 | 0.78 | MAPT (0.34) | MAPTDPP4ALDH1A1KMT2AMEN1 | |
| SCHEMBL1029075 | 0.78 | MAPT (0.59) | MAPTALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL557084 | 0.77 | CCR1 (0.43) | CRHBPCRHR2MAPTSLC40A1CYP3A4 | |
| SCHEMBL29533844 | 0.77 | CCR1 (0.43) | CRHBPCRHR2MAPTSLC40A1CYP3A4 | |
| SCHEMBL26999130 | 0.76 | CRHBP (0.40) | CRHBPCRHR2MAPTKMT2AMEN1 | |
| SCHEMBL114706 | 0.72 | KDM4E (0.58) | MAPTALDH1A1KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239239-B1 | IMPROVED CATALYST FOR POLYMERIZING OLEFINS | EQUISTAR CHEMICALS, L.P. | 2001-05-29 | — | — | US | disclosed |
| US-6020493-A | Single-site catalyst preparation | EQUISTAR CHEMICALS, LP (US) | 2000-02-01 | — | — | US | disclosed |