SCHEMBL28003189

SCHEMBL28003189

NC1(NC2(N)CCCCC2)CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16211022 0.79 TSHR (0.33) TSHRCYP2C19
SCHEMBL26431210 0.76
SCHEMBL1269163 0.73
SCHEMBL8074320 0.73 SLC6A4 (0.31) TSHRCYP2C19
SCHEMBL530925 0.73
SCHEMBL477423 0.72 HDAC4 (0.38) TSHRCYP2C19ALDH1A1
SCHEMBL15062781 0.72 ALDH1A1 (0.39) TSHRCYP2C19ALDH1A1
SCHEMBL21242398 0.70 HTT (0.40) TSHRCYP2C19ALDH1A1
SCHEMBL8414737 0.69 SLC6A3 (0.32)
SCHEMBL8088472 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104583258-A Polyurethane adhesives containing alkyl-substituted 4,4 ' -bis (aminocyclohexyl) alkanes, 2,4 ' -bis (aminocyclohexyl) alkanes and/or 2,2 ' -bis (aminocyclohexyl) amines DOW GLOBAL TECHNOLOGIES INC 2015-04-29 CN disclosed