SCHEMBL28004199

SCHEMBL28004199

COc1ccc(-c2nc(-c3ccccc3Cl)[nH]c2-c2ccc(OC)c(OC)c2)cc1OC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TEK Q02763 3/20 0.64
TP53 P04637 5/20 0.55
ALDH1A1 P00352 5/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 1/20 0.55
TSHR P16473 1/20 0.55
RAB9A P51151 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MAPT P10636 9/20 0.53
KDM4E B2RXH2 4/20 0.52
LMNA P02545 3/20 0.52
HPGD P15428 3/20 0.52
HTT P42858 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
NOX1 Q9Y5S8 2/20 0.51
THRB P10828 1/20 0.51
MPO P05164 1/20 0.50
SMPD3 Q9NY59 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29895756 0.96 TEK (0.59) TEKTP53ALDH1A1MEN1KMT2A
SCHEMBL9496039 0.96 TEK (0.59) TEKTP53ALDH1A1MEN1KMT2A
SCHEMBL29581646 0.96 TEK (0.59) TEKTP53ALDH1A1MEN1KMT2A
SCHEMBL5076359 0.95 TEK (0.57) TEKTP53ALDH1A1MEN1KMT2A
SCHEMBL1038907 0.92 TEK (0.58) TEKTP53ALDH1A1MEN1KMT2A
SCHEMBL28407375 0.88 MAPK13 (0.53) TEKTP53ALDH1A1MEN1KMT2A
Imidazole SCHEMBL7109750 0.86 TEK (0.55) TEKTP53ALDH1A1MEN1KMT2A
SCHEMBL9768433 0.83 NPY5R (0.51) TEKTP53ALDH1A1MEN1KMT2A
SCHEMBL28221004 0.83 MAPT (0.56) TP53ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL942701 0.82 TEK (0.70) TEKTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104471482-A Method for producing photosensitive resin element ASAHI KASEI E MATERIALS CORP 2015-03-25 CN disclosed