Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 8/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 2/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29895756 | 0.89 | TEK (0.59) | TEKMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL9496039 | 0.89 | TEK (0.59) | TEKMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL29581646 | 0.89 | TEK (0.59) | TEKMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL28004199 | 0.86 | TEK (0.64) | TEKALDH1A1TP53MEN1KMT2A | |
| Imidazole SCHEMBL5052057 | 0.83 | TEK (0.64) | TEKMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL28407375 | 0.82 | MAPK13 (0.53) | TEKMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL5076359 | 0.81 | TEK (0.57) | TEKALDH1A1TP53MEN1KMT2A | |
| SCHEMBL1038907 | 0.79 | TEK (0.58) | TEKMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL3194043 | 0.72 | TEK (0.50) | TEKMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL29375392 | 0.72 | TEK (0.50) | TEKMAPK14MAPK13RAF1MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1295180-A2 | PROCESS FOR PRODUCING MICROFLUIDIC ARTICLES | 3M Innovative Properties Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096958-A2 | PROCESS FOR PRODUCING MICROFLUIDIC ARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |