Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.59 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28003831 | 1.00 | HTR3A (0.59) | HTR3AJAK3SLC18A3SIGMAR1 | |
| SCHEMBL27815081 | 0.91 | HTR3A (0.49) | HTR3A | |
| SCHEMBL27489026 | 0.89 | SLC18A3 (0.55) | HTR3ASLC18A3SIGMAR1 | |
| SCHEMBL28672856 | 0.86 | HTR3A (0.56) | HTR3AJAK3 | |
| SCHEMBL27511207 | 0.83 | DRD2 (0.48) | HTR3ASLC18A3SIGMAR1 | |
| SCHEMBL23763865 | 0.81 | HTR3A (0.59) | HTR3AJAK3 | |
| SCHEMBL27469424 | 0.81 | HTR3A (0.59) | HTR3AJAK3 | |
| SCHEMBL28258195 | 0.81 | HTR3A (0.59) | HTR3AJAK3 | |
| SCHEMBL17825381 | 0.79 | HTR3A (0.56) | HTR3AJAK3 | |
| SCHEMBL5839498 | 0.79 | HTR3A (0.66) | HTR3AJAK3SLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104470918-A | Aromatic heterocyclic derivative and pharmaceutical | NIPPON SHINYAKU CO LTD | 2015-03-25 | — | — | CN | disclosed |