Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16870923 | 0.81 | DDR1 (0.41) | DDR1 | |
| SCHEMBL16648948 | 0.79 | DDR1 (0.47) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL3676457 | 0.79 | NPC1 (0.45) | MEN1NPC1RAB9AKMT2ALMNA | |
| SCHEMBL16867107 | 0.74 | DDR1 (0.46) | MEN1NPC1RAB9AKMT2ALMNA | |
| SCHEMBL20325638 | 0.74 | DDR1 (0.42) | DDR1 | |
| SCHEMBL20326611 | 0.72 | DDR1 (0.41) | PTGS2DDR1 | |
| SCHEMBL13791788 | 0.72 | MEN1 (0.40) | MEN1NPC1RAB9AKMT2ALMNA | |
| SCHEMBL3964486 | 0.72 | NOTUM (0.48) | MEN1NPC1RAB9AKMT2ALMNA | |
| SCHEMBL12013127 | 0.72 | RORC (0.54) | PTGS2RORCCA2 | |
| SCHEMBL21715818 | 0.71 | PTGS2 (0.41) | PTGS2DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379567-A | Fused heterocyclic compound | SUMITOMO CHEMICAL CO | 2015-02-25 | — | — | CN | disclosed |