Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 12/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20326611 | 0.93 | DDR1 (0.41) | DDR1GRIN2BPTGS1 | |
| SCHEMBL20325639 | 0.86 | GRIN2B (0.37) | DDR1GRIN2BPTGS1 | |
| SCHEMBL30989723 | 0.84 | DGAT1 (0.37) | DDR1GRIN2BALOX5APFEN1 | |
| SCHEMBL25885577 | 0.84 | DGAT1 (0.37) | DDR1GRIN2BALOX5APFEN1 | |
| SCHEMBL20326612 | 0.81 | GRIN2B (0.39) | DDR1GRIN2BPTGS1 | |
| SCHEMBL16648948 | 0.76 | DDR1 (0.47) | DDR1 | |
| SCHEMBL16870923 | 0.76 | DDR1 (0.41) | DDR1 | |
| SCHEMBL17504805 | 0.76 | USP1 (0.37) | DDR1PTGS1 | |
| SCHEMBL23013671 | 0.76 | DDR1 (0.58) | DDR1 | |
| SCHEMBL23013958 | 0.75 | DDR1 (0.44) | DDR1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200253210-A1 | Pesticidally Active Heterocyclic Derivatives With Sulphur Containing Substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-13 | — | — | US | disclosed |
| US-20200253210-A1 | Pesticidally Active Heterocyclic Derivatives With Sulphur Containing Substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-13 | — | — | US | disclosed |
| US-10667518-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-02 | — | — | US | disclosed |
| US-10667518-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-02 | — | — | US | disclosed |
| US-20190320657-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-24 | — | — | US | disclosed |
| US-20190320657-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-24 | — | — | US | disclosed |
| WO-2018113900-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10667518-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | DDT, ACHE, GSTM1 | DDR1 4516/4885GRIN2B 792/4885PTGS1 425/4885 |
| US-20200253210-A1 | Pesticidally Active Heterocyclic Derivatives With Sulphur Containing Substituents | DDT, ACHE, GSTM1 | DDR1 4516/4885GRIN2B 792/4885PTGS1 425/4885 |
| US-20190320657-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | DDR1 4516/4885GRIN2B 792/4885PTGS1 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.