⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671779 | 0.77 | — | — | |
| SCHEMBL1680245 | 0.72 | — | — | |
| SCHEMBL3872946 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL363546 | 0.72 | — | — | |
| SCHEMBL1121814 | 0.72 | — | — | |
| SCHEMBL9220394 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL7440333 | 0.70 | — | — | |
| SCHEMBL10641491 | 0.70 | L3MBTL1 (0.36) | — | |
| SCHEMBL5318623 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL13718807 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162441-B1 | 1,(3,)5-substituted imidazoles, useful in the treatment of hypertension and methods for their preparation | ELDRUG S A (GR) | 2016-01-06 | — | — | EP | disclosed |
| US-8563586-B2 | 1,(3,)5-substituted imidazoles, their use in the treatment of hypertension and methods for their preparation | ELDRUG S.A. (GR) | 2013-10-22 | — | — | US | disclosed |
| US-20100166837-A1 | 1,(3,)5-SUBSTITUTED IMIDAZOLES, THEIR USE IN THE TREATMENT OF HYPERTENSION AND METHODS FOR THEIR PREPARATION | ELDRUG S.A. (GR) | 2010-07-01 | — | — | US | disclosed |
| EP-2162441-A2 | 1,(3,)5-SUBSTITUTED IMIDAZOLES, THEIR USE IN THE TREATMENT OF HYPERTENSION AND METHODS FOR THEIR PREPARATION | Eldrug S.A. (GR) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008142576-A2 | 1,(3,)5-SUBSTITUTED IMIDAZOLES, THEIR USE IN THE TREATMENT OF HYPERTENSION AND METHODS FOR THEIR PREPARATION | ELDRUG S.A. (GR) | 2008-11-27 | — | — | WO | disclosed |
| EP-0040408-A1 | Beta-lactam compounds and process for production thereof | SANRAKU-OCEAN CO., LTD. (JP) | 1981-11-25 | — | — | EP | disclosed |