Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830959 | 0.92 | TSHR (0.40) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Maleic Acid SCHEMBL27997600 | 0.88 | HCAR2 (0.40) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28182877 | 0.88 | TSHR (0.37) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Methacrylic Acid SCHEMBL28013263 | 0.87 | TSHR (0.34) | TSHR | |
| Phosphoric Acid SCHEMBL27981627 | 0.86 | TSHR (0.36) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28015770 | 0.81 | TAAR1 (0.32) | TSHR | |
| Phthalic Acid SCHEMBL28015772 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HSD17B10 | |
| SCHEMBL11580487 | 0.79 | HCAR2 (0.39) | — | |
| SCHEMBL11580478 | 0.79 | HCAR2 (0.39) | — | |
| Succinic Acid SCHEMBL28045099 | 0.78 | TSHR (0.37) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102105546-B | Method for temporarily fixing/peeling member and adhesive suitable for temporary fixing | 电化株式会社 | 2016-12-07 | — | — | CN | disclosed |
| CN-103429720-B | For the friction improvement polymkeric substance of DLC coated surface | EVONIK ROHMAX ADDITIVES GMBH (DE) | 2016-03-16 | — | — | CN | disclosed |
| CN-103003400-B | Polyalkyl (meth) acrylate for improving lubricating oil properties | EVONIK ROHMAX ADDITIVES GMBH | 2015-05-06 | — | — | CN | disclosed |