Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195840 | 0.90 | TSHR (0.39) | TSHR | |
| SCHEMBL21409479 | 0.88 | TSHR (0.38) | TSHR | |
| Formic Acid SCHEMBL28861142 | 0.85 | TSHR (0.36) | TSHR | |
| Phosphoric Acid SCHEMBL27993219 | 0.83 | TSHR (0.35) | TSHR | |
| Succinic Acid SCHEMBL28005011 | 0.78 | TSHR (0.35) | TSHR | |
| SCHEMBL1770461 | 0.77 | TSHR (0.35) | TSHR | |
| SCHEMBL27953857 | 0.76 | ALDH1A1 (0.37) | TSHR | |
| Succinic Acid SCHEMBL4197612 | 0.75 | TSHR (0.44) | TSHRSLC6A2SLC6A4BLMSLC6A3 | |
| SCHEMBL891364 | 0.75 | HCAR2 (0.43) | — | |
| SCHEMBL891365 | 0.75 | HCAR2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110412840-A | Toner | CANON KK | 2019-11-05 | — | — | CN | disclosed |
| CN-105111823-B | The curable liquid and ink applied for toy and food packaging | 爱克发有限公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-103376681-B | Toner for developing electrostatic latent image | KONICA MINOLTA OPTO, INC. (JP) | 2015-12-02 | — | — | CN | disclosed |