Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005177 | 0.87 | PDGFRB (0.50) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28005174 | 0.86 | ADORA1 (0.50) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28005220 | 0.86 | TUBB4A (0.52) | ALDH1A1MAPTKDM4EADORA1MAPK1 | |
| SCHEMBL28005506 | 0.84 | SMN1; SMN2 (0.53) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28005543 | 0.84 | ADORA1 (0.48) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12802790 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28005182 | 0.82 | PDGFRB (0.51) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28005163 | 0.82 | FYN (0.59) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28005196 | 0.82 | TUBB4A (0.49) | ALDH1A1MAPTKDM4ECYP3A4ADORA1 | |
| SCHEMBL28005576 | 0.82 | KDM4E (0.50) | ALDH1A1MAPTKDM4ECYP3A4ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418821-A | 2, 4-substituted 5- (3,4, 5-trimethoxyphenyl) thiazole derivative and preparation method and application thereof | WEST CHINA HOSPITAL SICHUAN UNIV | 2015-03-18 | — | — | CN | claimed |
| CN-104418821-A | 2, 4-substituted 5- (3,4, 5-trimethoxyphenyl) thiazole derivative and preparation method and application thereof | WEST CHINA HOSPITAL SICHUAN UNIV | 2015-03-18 | — | — | CN | disclosed |