Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005543 | 0.90 | ADORA1 (0.48) | SMN1; SMN2ADORA1MAPTKDM4ELMNA | |
| SCHEMBL28005196 | 0.85 | TUBB4A (0.49) | SMN1; SMN2ADORA1MAPTKDM4ELMNA | |
| SCHEMBL28005179 | 0.84 | ALDH1A1 (0.62) | SMN1; SMN2ADORA1MAPTKDM4ELMNA | |
| SCHEMBL28005220 | 0.84 | TUBB4A (0.52) | SMN1; SMN2ADORA1MAPTKDM4ELMNA | |
| SCHEMBL28005576 | 0.80 | KDM4E (0.50) | SMN1; SMN2ADORA1MAPTKDM4ELMNA | |
| SCHEMBL28005177 | 0.80 | PDGFRB (0.50) | SMN1; SMN2ADORA1MAPTKDM4ELMNA | |
| SCHEMBL10120223 | 0.78 | KDM4E (0.56) | SMN1; SMN2ADORA1MAPTKDM4ELMNA | |
| SCHEMBL28005174 | 0.77 | ADORA1 (0.50) | SMN1; SMN2ADORA1MAPTKDM4ELMNA | |
| SCHEMBL5045105 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTKDM4ELMNAMAPK1 | |
| SCHEMBL10120710 | 0.75 | KDM4E (0.53) | SMN1; SMN2ADORA1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418821-A | 2, 4-substituted 5- (3,4, 5-trimethoxyphenyl) thiazole derivative and preparation method and application thereof | WEST CHINA HOSPITAL SICHUAN UNIV | 2015-03-18 | — | — | CN | claimed |
| CN-104418821-A | 2, 4-substituted 5- (3,4, 5-trimethoxyphenyl) thiazole derivative and preparation method and application thereof | WEST CHINA HOSPITAL SICHUAN UNIV | 2015-03-18 | — | — | CN | disclosed |