Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16415106 | 0.74 | KDM4E (0.52) | KDM4EGAAKEAP1HPGDALDH1A1 | |
| SCHEMBL2980135 | 0.74 | RAB9A (0.53) | KDM4EGAAKEAP1HPGDALDH1A1 | |
| SCHEMBL28778126 | 0.73 | KDM4E (0.47) | KDM4EGAAKEAP1HPGDALDH1A1 | |
| SCHEMBL4292232 | 0.73 | KDM4E (0.56) | KDM4EGAAKEAP1HPGDALDH1A1 | |
| SCHEMBL10978305 | 0.71 | ALDH1A1 (0.52) | KDM4EGAAKEAP1HPGDALDH1A1 | |
| SCHEMBL8913273 | 0.70 | KEAP1 (0.51) | KDM4EGAAKEAP1HPGDALDH1A1 | |
| SCHEMBL6583532 | 0.70 | KDM4E (0.62) | KDM4EGAAHPGDALDH1A1CYP3A4 | |
| SCHEMBL6750341 | 0.70 | KDM4E (0.53) | KDM4EGAAKEAP1HPGDALDH1A1 | |
| SCHEMBL28939376 | 0.70 | CA12 (0.56) | KDM4EGAAKEAP1HPGDALDH1A1 | |
| SCHEMBL17227605 | 0.70 | KEAP1 (0.47) | KDM4EGAAKEAP1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107148574-A | For instructing the major adverse cardiac event in subject or the hGH of the prevention of angiocardiopathy to determine | 思芬构技术有限公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-104603214-B | Ink and method for ink-jet printing textile fibre materials | 亨斯迈先进材料（瑞士）有限公司 | 2017-08-08 | — | — | CN | disclosed |
| CN-102575287-B | Methods and compositions involving ALK fusions for diagnosis and treatment of cancer | 因赛特遗传学公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-104603214-A | Ink and method for ink-jet printing textile fibre materials | HUNTSMAN ADV MAT SWITZERLAND | 2015-05-06 | — | — | CN | disclosed |